Permethrin-induced oxidative damage in liver of rainbow trout (Oncorhynchus mykiss) and its attenuation by vitamin C

Authors

  • A. Moghadam Jafari Department of Basic Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran
  • M. Heidarpour Department of Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran
  • M.K. Koohi Department of Basic Sciences, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
  • Z. Mozhdeganloo Post-Graduate Student, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
Abstract:

The objective of this study was to investigate the propensity of permethrin (PTN) to induce oxidative stress and changes in enzyme activities in liver of rainbow trout and its possible attenuation by vitamin C. Forty-eight fish were randomly assigned to 1 of 6 treatment groups and their livers were used for liver perfusion method: control (0 μgL-1 permethrin and 0 mgL-1 vitamin C), PTN-0.16 (0.16 μgL-1 permethrin), PTN-0.32 (0.32 μgL-1 permethrin), PTN-0.64 (0.64 μgL-1 permethrin), Vit. C (17.2 mgL-1 vitamin C), and PTN-0.64 + Vit. C (0.64 μgL-1 permethrin and 17.2 mgL-1 vitamin C). Results obtained showed that permethrin significantly (P

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Permethrin-induced oxidative damage in liver of rainbow trout (Oncorhynchus mykiss) and its attenuation by vitamin C.

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Journal title

volume 17  issue 1

pages  31- 35

publication date 2016-03-01

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